You’ll want quick clarity: a 17-year-old defendant says a prescribed acne medication helped trigger the violent episode that killed his friend, and his legal team argues those side effects should factor into criminal responsibility. You’ll follow how the shooting unfolded, how prosecutors and defense experts clash over medication-linked psychiatric effects, and what this case could mean for future “Rx defenses.”
This piece maps the timeline and legal fallout, then examines medical evidence and contested links between isotretinoin and severe mood changes. Expect factual reporting, competing expert views, and implications for law and prescribing practice.
For background on the case and the medication implicated, see reporting from the New York Post and a detailed account by CBS News.
Shooting Incident and Legal Aftermath

The shooting killed one teen and gravely wounded another. The defendant later said prescription acne medication changed his thoughts, and the case moved quickly from arrest to a contested trial posture and eventual plea.
Timeline of the Friendswood Shooting
On a December night in 2023, 17-year-old Connor Hilton shot two friends at a residence in Friendswood, Texas. Emergency responders arrived after a 911 call; one victim had life-threatening injuries and the other was critically wounded.
Police took Hilton into custody soon afterward. Authorities charged him with murder and aggravated assault with a deadly weapon under Texas law. Local reporting and court filings established the basic sequence: the shooting, medical transport, and Hilton’s prompt arrest.
Court scheduling followed criminal procedure in the state, including detention hearings and pretrial motions. Media reports tracked the case as the defense prepared a medication-related theory while prosecutors pursued the statutory charges.
Connor Hilton’s Confession and Arrest
Hilton admitted to police that he shot both friends, according to public reporting. Investigators recorded statements that became central to the prosecution’s case and to later courtroom arguments about motive and mental state.
His defense team later framed his actions as tied to severe side effects from isotretinoin, a prescription acne medication. The defense sought to introduce expert psychiatric testimony about medication-induced suicidal or homicidal ideation; a judge later limited or rejected portions of that testimony, affecting trial strategy.
Prosecutors emphasized the admissions and the deadly nature of the act to support murder and aggravated assault counts. Bail, detention status, and pretrial custody details followed standard state procedures while both sides prepared for trial.
Victims: Ethan Riley and Benjamin Bliek
Ethan Riley, 18, died from his wounds; reporting identified him as the fatality in the incident. Family statements and local coverage described the loss and the community’s response to his death.
Benjamin Bliek survived but sustained grave injuries. Medical accounts and news coverage noted his critical condition and subsequent recovery efforts. Both victims had been friends with Hilton, which amplified local shock and raised questions about motive and prior interactions.
Victim impact details appeared in court filings and press reports, informing sentencing considerations. Community memorials and family comments were part of public coverage as the legal process unfolded.
Trial, Guilty Plea, and Sentencing
Hilton initially faced trial plans that included contested expert testimony about medication effects. A judge ruled against allowing certain psychiatric testimony linking isotretinoin directly to homicidal behavior, forcing the defense to adjust strategy. Coverage of that ruling noted its impact on the admissibility of the medication-defense theory.
Rather than proceed to a full jury trial on all contested issues, Hilton later entered a guilty plea to charges including murder and aggravated assault with a deadly weapon. Plea terms and any agreed facts were entered on the record in state court.
The court moved to sentencing under Texas statutes for murder and aggravated assault. Sentencing hearings considered victim impact, Hilton’s statements, and the contested role of medication in his defense. Media reports and court documents recorded the outcomes and any imposed penalties.
Medication, Mental Health, and the ‘Rx Defense’
This section explains what isotretinoin is and how opponents and courts treat claims that it caused severe psychiatric effects. It outlines reported side effects, how experts address causation, and how the case entered public view through broadcast coverage.
Accutane and Isotretinoin: Uses and Risks
Isotretinoin, commonly known by the brand name Accutane, treats severe, recalcitrant acne by reducing sebaceous gland activity and inflammation. Physicians prescribe it when other therapies fail because it reliably decreases lesion count and scarring.
The drug carries well-documented systemic risks. Teratogenicity requires strict pregnancy-prevention programs. Common short-term effects include dry skin and cheilitis; rarer effects reported in case series and regulatory reviews include mood changes and severe psychiatric symptoms. Patients receive informed-consent counseling and monitoring recommendations to watch for mood or behavior changes while on therapy.
Psychiatric Side Effects: Depression, Psychosis, and Violent Behavior
Reports and post-marketing surveillance have linked isotretinoin to mood changes, depressive symptoms, and, in isolated cases, psychosis or suicidal ideation. Large epidemiologic studies find mixed results: some show small increased risk signals, others show no clear increase after adjusting for underlying acne severity and confounders.
Clinicians emphasize differential diagnosis. Acne itself, social stigma, and preexisting mental-health conditions can produce depression or impulse control problems. Establishing direct causation for homicidal or violent behavior requires temporal correlation, dechallenge/rechallenge data, and exclusion of other causes. Courts and experts scrutinize timelines, medical records, and psychiatric histories when assessing whether medication plausibly produced severe behavioral disturbance.
Expert Testimony and Court Rulings
Defense teams sometimes use an involuntary-intoxication or medication-induced-psychosis argument—often called an “Rx defense”—to explain criminal acts. Forensic experts review prescription records, dosing, onset of symptoms, and alternative explanations before offering opinions to a judge or jury.
Courts evaluate such testimony under evidentiary rules that require reliable methods and relevance. Judges may admit expert opinions about medication effects if grounded in peer-reviewed literature and case-specific evidence. Opposing experts commonly argue that correlation does not equal causation and highlight other risk factors. Outcomes vary: some defendants obtain mitigation or alternative sentencing tied to treatment needs; others face conviction when the causal link remains unproven.
Media Spotlight: CBS News ’48 Hours’ and The Rx Defense
Broadcast investigations have amplified public attention to medication-related defenses. A recent episode of CBS News’ 48 Hours examined a teenager who confessed to shooting friends while his defense contends isotretinoin contributed to homicidal thoughts. The program presented interviews, police audio, and medical commentary to frame the question of medication influence.
Media coverage can shape public perception and legal strategy by highlighting expert disagreement and by giving lay audiences medical context. The show referenced testimony from practitioners such as Dr. Doug Bremner, who has provided opinions linking isotretinoin to psychiatric effects in some cases. Viewers should note that televised reporting summarizes complex forensic and medical evidence rather than deciding legal causation.
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